Cohort Characteristics

March 2, 2020

The study cohort consisted of 12,610 participants. Of those enrolled, 8,974 were initially HIV-negative, 3,596 were HIV-positive, and 40 refused HIV testing.

Baseline characteristics of trial participants at enrollment to Ya Tsie Household Survey according to randomization arm, 2013-2015*

Baseline HIV Prevalence

Among the 12,610 participants enrolled in the household survey, 3,596 were HIV-positive, indicating an average HIV prevalence of 29% across the 30 communities for the 16-64 year old age group.There was a wide range of variability in HIV prevalence across study communities, ranging from 16% at the low end to 45% at the high end.

Prevalence by Age and Sex

Progress Towards UNAIDS 90-90-90 Targets

In 2014, UNAIDS proposed new testing and treatment targets directed towards ending the AIDS epidemic. The ambitious targets, with a target date of 2020, called for 90% of all people living with HIV to know their HIV status; 90% of all people diagnosed with HIV to receive ART; and 90% of all people receiving ART to achieve viral suppression. 

Data collected for our Baseline Household Survey showed that by the end of 2015, Botswana was close to achieving the UNAIDS 90-90-90 targets.

Of the 12,570 study participants surveyed and tested for HIV at baseline (before the study intervention), 3,596 (29%) were living with HIV. Of those living with HIV, 2,995 (83%) already knew their HIV status. Among those who knew about their positive status, 2,617 (87%) were receiving ART. Of the 2,609 individuals receiving ART who had a verifiable viral load test, 2,517 (96%) had a suppressed HIV viral load.

Very few countries, including the U.S., have come close to Botswana’s exceptional treatment coverage.