Efficacy of Human Papillomavirus (HPV) Vaccination to Prevent Infection Among Women Living with HIV: A Prospective, Individual, Double-Blind, Randomized Controlled Study (HOPE-II)
Principal Investigator Initiated

Principal Investigator: Dr Rebecca Luckett, MD, MPH

Study Objectives:

Primary Objective:

Equitable access to care for migrants living with HIV in Southern Africa: Lessons learnt from Botswana’s migrant inclusive program
Principal Investigator Initiated

Principal Investigator: Dr Tafireyi Marukutira, MD, PhD, MPH

Study Objectives:

Primary Objective:

Evaluating Opportunities to Improve TB and HIV Care for Adolescents in Botswana
Principal Investigator Initiated

Study Objectives

Evaluation of pregnant and breastfeeding women’s preferences and attitudes towards long-acting pre-exposure prophylaxis: A discrete choice experiment. MERCK
Principal Investigator Initiated

Principal Investigator: Chelsea Morroni, MPH, MPhil, PhD, MBChB, DTM&H, DFSRH

Study Objectives:

Objective 1

Experiences of Infant Feeding Decision-Making among Mothers Living with and without HIV in Botswana
Principal Investigator Initiated

Principal Investigator: Roxanna Haghighat, DPhil | Kathleen Powis, MD, MPH, MBA

Study Objectives

Exploring the Acceptability and Feasibility of COVID19 Testing among Truck Drivers in Botswana
Principal Investigator Initiated

Principal Investigator - Nabila Youssouf PhD | Laura Bogart | Mosepele Mosepele MD, MSc

Name of the Study: Exploring the Acceptability and Feasibility of COVID19 Testing among Truck Drivers in Botswana

Study Status: Completed recruitment – data analysis ongoing

Study Objectives: To explore the acceptability and feasibility on COVID 19 testing among truck drivers entering Botswana and to acquire feedback about potential interventions to further respond to this evolving crisis. 

Feasibility and Accuracy of Nanosenor-based cancer diagnosis at the point of care (Chedza Study).
Principal Investigator Initiated

Principal Investigator - Dr. Scott Dryden-Peterson, MD, MSc

FLOURISH: Following Longitudinal Outcomes to Understand, Report, Intervene and Sustain Health for Infants, Children, Adolescents who are HIV Exposed Uninfected
Principal Investigator Initiated

Principal Investigators - Dr. Kathleen M. Powis, MD, MPH, MBA | Dr. Jennifer Jao, MD, MPH | Dr. Joseph Makhema, MB.ChB, FRCP

Study Objectives 

Primary Study Aims

Genomic epidemiology of Treponema pallidum in South Africa and Botswana
Principal Investigator Initiated

Principal Investigator: Chelsea Morroni, MPH, MPhil, PhD, MBChB, DTM&H, DFSRH

Study Objectives:

HIV and Malignancy in Botswana: An observational Study of Medicine Toxicity of Concurrent Treatment and Clinical Outcomes (Thabatse Study)
Principal Investigator Initiated

Principal Investigator - Dr. Scott Dryden-Peterson MD, MSc

Thabatse is a prospective cohort study which aims to evaluate the risk factors for cancer and describe the response to treatment for patients who are HIV positive and not on Antiretroviral Therapy (ART) and those on ART.

Study Objectives

The primary aims are to evaluate the important risk factors for cancer in Botswana (including HIV) and describe the response to treatment for patients without HIV, with HIV but not yet on HAART, and those with HIV and on HAART.

HPV Screening and Management Strategies Utilizing Extended Molecular HPV DNA Genotyping and Viral Load in Women Living with HIV
Principal Investigator Initiated

Principal Investigators:

1. Doreen Ramogola-Masire, PhD, MSc, FCOG, BMBS, BMedSci

2. Scott Dryden-Peterson, MD, MSc

Human Papillomavirus (HPV) Cervical Cancer Screening Study
Principal Investigator Initiated

Principal Investigator - Dr. Rebecca Luckett, MD, MPH

Name of the Study: Evaluation of cervical cancer screening algorithms using primary high risk human papillomavirus (HPV) in Gaborone and South East District, Botswana

Completed: Recruitment of 300 women living with HIV in Gaborone, and one year follow-up of this cohort. 

On-going: Recruitment of a new cohort of 3000 women in South East District is currently underway. 50% of the cohort will be women living with HIV. 

IMPRINT NIHR Global Health Research Group
Principal Investigator Initiated

Study Objectives: The group aims to improve the diagnosis and treatment of the four major HIV-associated fungal infections of public health importance and to ensure that these improvements are made widely available to populations most commonly affected in Africa (Democratic Republic of Congo, Mozambique, Guinea, Malawi, Botswana, South Africa), and South East Asia (Vietnam). The group brings together leading academic rese

Improving TB Screening in Pregnant and Postpartum Women Living with HIV in Botswana
Principal Investigator Initiated

Principal Investigator - Melanie Dubois, MD

Study Objectives:

In Country Evaluation for the ANC panel
Principal Investigator Initiated

Study Objectives:

The primary aim of this study is to evaluate the sensitivity and specificity of the Abbot ANC panel and its usability by trained Healthcare Professionals in a non-laboratory setting.

Increasing Access to Multiple Micronutrient Supplementation – A Pilot Intervention at up to 15 Clinics in Botswana
Principal Investigator Initiated

Principal Investigator: Dr. Ellen Caniglia, ScD

Study Objectives

Innovative HIV Testing Strategy for Middle-to-Upper Income Men in a Resource-Limited Setting
Principal Investigator Initiated

Principal Investigator - Professor Mosepele Mosepele MD, MSc, | Laura Bogart PhD

Study Objectives:

Integrating Hypertension and Cardiovascular Diseases Care into Existing HIV Services Package in Botswana (InterCARE Study)
Principal Investigator Initiated

Principal Investigators - Professor Mosepele Mosepele MD, MSc | Tendani Gaolathe BS, MD | Kathleen Wirth Hurwitz

International Sexual Health and Reproductive (ISHARE) Health Survey During COVID-19
Principal Investigator Initiated

Principal Investigator - Dr. Chelsea Morroni, MD, MPH, PhD

Iron and Folic acid supplimentation and adverse birth outcomes in Botswana
Principal Investigator Initiated

Principal Investigator: Ellen Caniglia, ScD

Study iron, folic acid and multiple micronutrient supplementation and adverse birth outcomes in Botswana began in 2020.