Name of the study: The diagnosis and treatment of Chlamydia trachomatis and Neisseria gonorrhoeae in pregnant women to prevent adverse neonatal consequences (Maduo Study).
Study Status: Recruiting
- To determine the burden of CT/NG infections and correlates of infection among asymptomatic pregnant women in Gaborone, Botswana.
- To compare longitudinal neonatal outcomes for pregnant women tested & treated for CT/NG infections during antenatal care with women who received standard antenatal care.
- To assess the burden of infection and markers of inflammatory response to CT/NG infection during pregnancy and associations with vertical transmission of CT/NG.
Study Design: Cohort study
Study Population: Pregnant women (aged >=15 years) attending their first antenatal care visit at 27 weeks’ gestation or less who have not been treated for an STI within the last 30 days.
Study Size: 500 participants (250 in the testing group and 250 in the standard of care group).
Study Duration: 2 years
Sponsor: National Institutes of Health (NIH)