HIV-1 Subtype C Drug Resistance Mutations in Heavily Treated Patients Failing Integrase Strand Transfer Inhibitor-Based Regimens in Botswana
Authors
Kaelo K Seatla, Dorcas Maruapula, Wonderful T Choga, Tshenolo Ntsipe, Nametso Mathiba, Mompati Mogwele, Max Kapanda, Bornapate Nkomo, Dinah Ramaabya, Joseph Makhema, Mompati Mmalane, Madisa Mine, Ishmael Kasvosve, Shahin Lockman, Sikhulile Moyo, Simani Gaseitsiwe

Journal : Viruses

DOI : 10.3390/v13040594

PMCID : PMC8066386

PMID : 33807382

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Using a dual antibody point-of-care test with visual and digital reads to diagnose syphilis among people living with HIV in Botswana
Authors
Irfaan Maan, David S Lawrence, Nametso Tlhako, Kehumile Ramontshonyana, Aamirah Mussa, Adriane Wynn, Michael Marks, Doreen Ramogola-Masire, Chelsea Morroni

Journal : Int J STD AIDS

DOI : 10.1177/0956462420975639

PMCID : PMC8008391

PMID : 33570464

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Pharmacokinetics and Drug-Drug Interactions of Isoniazid and Efavirenz in Pregnant Women Living With HIV in High TB Incidence Settings: Importance of Genotyping
Authors
Kamunkhwala Gausi, Lubbe Wiesner, Jennifer Norman, Carole L Wallis, Carolyne Onyango-Makumbi, Tsungai Chipato, David W Haas, Renee Browning, Nahida Chakhtoura, Grace Montepiedra, Lisa Aaron, Katie McCarthy, Sarah Bradford, Tichaona Vhembo, Lynda Stranix-Chibanda, Gaerolwe R Masheto, Avy Violari, Blandina T Mmbaga, Linda Aurpibul, Ramesh Bhosale, Neetal Nevrekhar, Vanessa Rouzier, Enid Kabugho, Mercy Mutambanengwe, Vongai Chanaiwa, Mandisa Nyati, Tsungai Mhembere, Fuanglada Tongprasert, Anneke Hesseling, Katherine Shin, Bonnie Zimmer, Diane Costello, Patrick Jean-Philippe, Timothy R Sterling, Gerhard Theron, Adriana Weinberg, Amita Gupta, Paolo Denti, IMPAACT P1078 (TB APPRISE) Study Group Team

Journal : Clin Pharmacol Ther

DOI : 10.1002/cpt.2044

PMCID : PMC8048881

PMID : 32909316

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Efficacy and safety of dolutegravir with emtricitabine and tenofovir alafenamide fumarate or tenofovir disoproxil fumarate, and efavirenz, emtricitabine, and tenofovir disoproxil fumarate HIV antiretroviral therapy regimens started in pregnancy
Authors
Shahin Lockman, Sean S Brummel, Lauren Ziemba, Lynda Stranix-Chibanda, Katie McCarthy, Anne Coletti, Patrick Jean-Philippe, Ben Johnston, Chelsea Krotje, Lee Fairlie, Risa M Hoffman, Paul E Sax, Sikhulile Moyo, Nahida Chakhtoura, Jeffrey Sa Stringer, Gaerolwe Masheto, Violet Korutaro, Haseena Cassim, Blandina T Mmbaga, Esau João, Sherika Hanley, Lynette Purdue, Lewis B Holmes, Jeremiah D Momper, Roger L Shapiro, Navdeep K Thoofer, James F Rooney, Lisa M Frenkel, K Rivet Amico, Lameck Chinula, Judith Currier, IMPAACT 2010/VESTED Study Team and Investigators

Journal : Lancet

DOI : 10.1016/S0140-6736(21)00314-7

PMCID : PMC8132194

PMID : 33812487

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The Lived Experience Of Participants in an African RandomiseD trial (LEOPARD): protocol for an in-depth qualitative study within a multisite randomised controlled trial for HIV-associated cryptococcal meningitis
Authors
David S Lawrence, Katlego Tsholo, Agnes Ssali, Zivai Mupambireyi, Graeme Hoddinott, Deborah Nyirenda, David B Meya, Chiratidzo Ndhlovu, Thomas S Harrison, Joseph N Jarvis, Janet Seeley

Journal : BMJ Open

DOI : 10.1136/bmjopen-2020-039191

PMCID : PMC8030472

PMID : 33820784

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Development of an international sexual and reproductive health survey instrument: results from a pilot WHO/HRP consultative Delphi process
Authors
Eneyi E Kpokiri, Dan Wu, Megan L Srinivas, Juliana Anderson, Lale Say, Osmo Kontula, Noor A Ahmad, Chelsea Morroni, Chimaraoke Izugbara, Richard de Visser, Georgina Y Oduro, Evelyn Gitau, Alice Welbourn, Michele Andrasik, Wendy V Norman, Soazig Clifton, Amanda Gabster, Amanda Gesselman, Chantal Smith, Nicole Prause, Adesola Olumide, Jennifer T Erausquin, Peter Muriuki, Ariane van der Straten, Martha Nicholson, Kathryn A O'Connell, Meggie Mwoka, Nathalie Bajos, Catherine H Mercer, Lianne Marie Gonsalves, Joseph D Tucker

DOI : 10.1136/sextrans-2020-054822

PMCID : PMC8785043

PMID : 33846277

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Enhanced and Timely Investigation of ARVs for Use in Pregnant Women
Authors
Elaine J Abrams, Lynne M Mofenson, Anton Pozniak, Shahin Lockman, Angela Colbers, Yodit Belew, Polly Clayden, Mark Mirochnick, George K Siberry, Nathan For, Saye Khoo, Francoise Renaud, Marco Vitoria, Willem D F Venter, Meg Doherty, Martina Penazzato, PADO and CADO Experts Groups

Journal : J Acquir Immune Defic Syndr

DOI : 10.1097/QAI.0000000000002597

PMID : 33298793

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Finding, treating and retaining persons with HIV in a high HIV prevalence and high treatment coverage country: Results from the Botswana Combination Prevention Project
Authors
Pamela Bachanas, Mary Grace Alwano, Refeletswe Lebelonyane, Lisa Block, Stephanie Behel, Elliot Raizes, Gene Ussery, Huisheng Wang, Faith Ussery, Molly Pretorius Holme, Connie Sexton, Sherri Pals, Arielle Lasry, Lisetta Del Castillo, Shannon Hader, Shahin Lockman, Naomi Bock, Janet Moore

Journal : PLoS One

DOI : 10.1371/journal.pone.0250211

PMCID : PMC8059857

PMID : 33882092

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Outcomes of Reflex Cryptococcal Antigen (CrAg) Screening in Human Immunodeficiency Virus (HIV)-Positive Patients With CD4 Counts of 100-200 Cells/µL in Botswana
Authors
Mark W Tenforde, Thandi Milton, Ikanyeng Rulaganyang, Charles Muthoga, Leabaneng Tawe, Tom Chiller, Gregory Greene, Alexander Jordan, Christopher G Williams, Leah Owen, Tshepo B Leeme, Amber Boose, Julia Ngidi, Madisa Mine, Joseph N Jarvis

DOI : 10.1093/cid/ciaa899

PMCID : PMC8096249

PMID : 32604411

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Lower birth weight-for-age and length-for-age z-scores in infants with in-utero HIV and ART exposure: a prospective study in Cape Town, South Africa
Authors
Dorothy C Nyemba, Emma Kalk, Hlengiwe P Madlala, Thokozile R Malaba, Amy L Slogrove, Mary-Ann Davies, Andrew Boulle, Landon Myer, Kathleen M Powis

Journal : BMC Pregnancy Childbirth

DOI : 10.1186/s12884-021-03836-z

PMCID : PMC8097797

PMID : 33947351

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Use of a mutation-specific genotyping method to assess for HIV-1 drug resistance in antiretroviral-naïve HIV-1 Subtype C-infected patients in Botswana
Authors
Dorcas Maruapula, Iain J MacLeod, Sikhulile Moyo, Rosemary Musonda, Kaelo Seatla, Kesaobaka Molebatsi, Melvin Leteane, Max Essex, Simani Gaseitsiwe, Christopher F Rowley

DOI : 10.12688/aasopenres.13107.2

PMCID : PMC8112461

PMID : 34036243

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Prevalence and Sequelae of Cryptococcal Antigenemia in Antiretroviral Therapy-Experienced Populations: An Evaluation of Reflex Cryptococcal Antigen Screening in Botswana
Authors
William J Hurt, Mark W Tenforde, Mooketsi Molefi, Hannah K Mitchell, Thandi Milton, Martin S Azama, Irene Goercke, Fredah Mulenga, Nametso Tlhako, Katlego Tsholo, Tuhina Srivastava, Tshepo B Leeme, Godfrey Simoonga, Charles Muthoga, Kwana Lechiile, Madisa Min, Joseph N Jarvis

DOI : 10.1093/cid/ciaa356

PMCID : PMC8130030

PMID : 32236414

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Equity in clinical trials for HIV-associated cryptococcal meningitis: A systematic review of global representation and inclusion of patients and researchers
Authors
David S Lawrence, Tshepo Leeme, Mosepele Mosepele, Thomas S Harrison, Janet Seeley, Joseph N Jarvis

Journal : PLoS Negl Trop Dis

DOI : 10.1371/journal.pntd.0009376

PMCID : PMC8158913

PMID : 34043617

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Individual and Composite Adverse Pregnancy Outcomes in a Randomized Trial on Isoniazid Preventative Therapy Among Women Living With Human Immunodeficiency Virus
Authors
Gerhard Theron, Grace Montepiedra, Lisa Aaron, Katie McCarthy, Nahida Chakhtoura, Patrick Jean-Philippe, Bonnie Zimmer, Amy James Loftis, Tsungai Chipato, Teacler Nematadzira, Mandisa Nyati, Carolyne Onyango-Makumbi, Gaerolwe Masheto, James Ngocho, Fuanglada Tongprasert, Sandesh Patil, Dominique Lespinasse, Adriana Weinberg, Amita Gupta

DOI : 10.1093/cid/ciaa1482

PMCID : PMC8315231

PMID : 32997744

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Modest reduction in adverse birth outcomes following the COVID-19 lockdown
Authors
Ellen C Caniglia, Lerato E Magosi, Rebecca Zash, Modiegi Diseko, Gloria Mayondi, Judith Mabuta, Kathleen Powis, Scott Dryden-Peterson, Mosepele Mosepele, Rebecca Luckett, Joseph Makhema, Mompati Mmalane, Shahin Lockman, Roger Shapiro

Journal : Am J Obstet Gynecol

DOI : 10.1016/j.ajog.2020.12.1198

PMCID : PMC7817370

PMID : 33347842

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