Publications Date
Authors
Iwase SC, Edlefsen PT, Bhebhe L, Motsumi K, Moyo S, Happel AU, Shao D, Mmasa N, Schenkel S, Gasper MA, Dubois M, Files MA, Seshadri C, Duffy F, Aitchison J, Netea MG, Jao J, Cameron DW, Gray CM, Jaspan HB, Powis KM.
Journal
Clin Infect Dis.
PMID
37293702
DOI
doi: 10.1093/cid/ciad356
Abstract

Infants who are human immunodeficiency virus (HIV)-exposed uninfected (iHEU) experience higher risk of infectious morbidity than infants HIV-unexposed uninfected (iHUU). We compared tuberculosis (TB) infection prevalence in 418 Bacillus Calmette-Guérin vaccinated sub-Saharan African iHEU and iHUU aged 9-18 months using T-SPOT.TB. Prevalence of TB infection was low and did not differ by HIV exposure status.

Keywords: HIV exposure; Southern Africa; T-SPOT.TB; TB infection; infants.

 

Copyright/License
© The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America.
T-SPOT.TB reactivity in Southern African children with and without in utero HIV…